Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast

Title: Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast

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Abstract

The present invention provides isolated gene sequences useful in increasing lignocellulosic toxin tolerance in yeast. Such engineered yeast are useful in methods of biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast with increased lignocellulosic toxin tolerance are also provided.

Inventors:: Sardi, Maria; Gasch, Audrey P.

Issue Date:: 2019-10-15

Research Org.:: Wisconsin Alumni Research Foundation, Madison, WI (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1600148

Patent Number(s):: 10443062

Application Number:: 15/693,710

Assignee:: Wisconsin Alumni Research Foundation (Madison, WI)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C12Y101/0117 - 3Beta-hydroxy-4alpha-carboxy-sterol 3-dehydrogenase
C12Y207/01025 - Adenylyl-sulfate kinase

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N9/0006 - {acting on CH-OH groups as donors
C12N15/81 - for yeasts

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C07K14/395 - from Saccharomyces

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/10 - Biofuels

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P7/10 - substrate containing cellulosic material
C12P7/649 - {Biodiesel, i.e. Fatty acid alkyl esters}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/30 - Fuel from waste

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N15/52 - Genes encoding for enzymes or proenzymes
C12N9/1205 - {Phosphotransferases with an alcohol group as acceptor

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DOE Contract Number:: FC02-07ER64494

Resource Type:: Patent

Resource Relation:: Patent File Date: 09/01/2017

Country of Publication:: United States

Language:: English

Subject:: 09 BIOMASS FUELS; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Sardi, Maria, and Gasch, Audrey P. Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast.  United States: N. p., 2019. 
        Web.

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                    Sardi, Maria, & Gasch, Audrey P. Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast.  United States.

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                    Sardi, Maria, and Gasch, Audrey P. Tue .  
        "Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast".  United States.  https://www.osti.gov/servlets/purl/1600148.

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@article{osti_1600148,

  title        = {Genes that improve tolerance to lignocellulosic toxins when overexpressed in yeast},

  author       = {Sardi, Maria and Gasch, Audrey P.},

  abstractNote = {The present invention provides isolated gene sequences useful in increasing lignocellulosic toxin tolerance in yeast. Such engineered yeast are useful in methods of biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast with increased lignocellulosic toxin tolerance are also provided.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2019},

  month        = {10}

}

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