Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use
Abstract
The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for gamma valerolactone (GVL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved GVL-mediated hydrolysis of lignocellulosic biomass for industrial-scale ethanol production.
- Inventors:
- Issue Date:
- Research Org.:
- Wisconsin Alumni Research Foundation, Madison, WI (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1460543
- Patent Number(s):
- 10006057
- Application Number:
- 14/848,440
- Assignee:
- Wisconsin Alumni Research Foundation (Madison, WI)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- FC02-07ER64494
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Sep 09
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Piotrowski, Jeff S., Sato, Trey K., and Myers, Chad L. Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use. United States: N. p., 2018.
Web.
Piotrowski, Jeff S., Sato, Trey K., & Myers, Chad L. Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use. United States.
Piotrowski, Jeff S., Sato, Trey K., and Myers, Chad L. Tue .
"Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use". United States. https://www.osti.gov/servlets/purl/1460543.
@article{osti_1460543,
title = {Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use},
author = {Piotrowski, Jeff S. and Sato, Trey K. and Myers, Chad L.},
abstractNote = {The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for gamma valerolactone (GVL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved GVL-mediated hydrolysis of lignocellulosic biomass for industrial-scale ethanol production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {6}
}
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