Process for the production of 18F-2-deoxy-2-fluoro-D-glucose
Abstract
Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding 18F-compound by the reaction of acetyl hypofluorite or the corresponding 18F-compound with 3,4,6-tri-O-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.
- Inventors:
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176553
- Patent Number(s):
- H000074
- Application Number:
- 06/469597
- Assignee:
- The United States of America as represented by the United States Department of Energy (Washington, DC)
- DOE Contract Number:
- AC02-76CH00016
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1983 Feb 24
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; statutory invention registration
Citation Formats
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., and MacGregor, Robert R. Process for the production of 18F-2-deoxy-2-fluoro-D-glucose. United States: N. p., 1986.
Web.
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., & MacGregor, Robert R. Process for the production of 18F-2-deoxy-2-fluoro-D-glucose. United States.
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., and MacGregor, Robert R. Tue .
"Process for the production of 18F-2-deoxy-2-fluoro-D-glucose". United States. https://www.osti.gov/servlets/purl/1176553.
@article{osti_1176553,
title = {Process for the production of 18F-2-deoxy-2-fluoro-D-glucose},
author = {Shiue, Chyng-Yann and Salvadori, Piero A. and Wolf, Alfred P. and Fowler, Joanna S. and MacGregor, Robert R.},
abstractNote = {Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding 18F-compound by the reaction of acetyl hypofluorite or the corresponding 18F-compound with 3,4,6-tri-O-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 06 00:00:00 EDT 1986},
month = {Tue May 06 00:00:00 EDT 1986}
}
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Works referenced in this record:
Author index for volume 22
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Acetyl hypofluorite, the first member of a new family of organic compounds
journal, January 1981
- Rozen, Shlomo; Lerman, Ori; Kol, Moshe
- Journal of the Chemical Society, Chemical Communications, Issue 10
Fluorination with molecular fluorine. A convenient synthesis of 2-deoxy-2-fluoro-D-glucose
journal, June 1977
- Ido, T.; Wan, C. N.; Fowler, J. S.
- The Journal of Organic Chemistry, Vol. 42, Issue 13
A rapid, stereospecific synthesis of 2-deoxy-2-fluoro-D-glucose using the fluoride ion
journal, January 1982
- Szarek, Walter A.; Hay, George W.; Perlmutter, Milton M.
- Journal of the Chemical Society, Chemical Communications, Issue 21