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Title: Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose

Abstract

Process is given for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding /sup 18/F-compound by the reaction of acetyl hypofluorite or the corresponding /sup 18/F-compound with 3,4,6-tri-0-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.

Inventors:
; ; ; ;
OSTI Identifier:
5446138
Application Number:
ON: DE84006187
Assignee:
EDB-84-030565
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; GLUCOSE; LABELLING; FLUORINE 18; ORGANIC FLUORINE COMPOUNDS; ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOHYDRATES; FLUORINE ISOTOPES; HEXOSES; HOURS LIVING RADIOISOTOPES; ISOTOPES; LIGHT NUCLEI; MONOSACCHARIDES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOISOTOPES; SACCHARIDES; 400702* - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials

Citation Formats

Shiue, C Y, Salvadori, P A, Wolf, A P, Fowler, J S, and MacGregor, R R. Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose. United States: N. p., Web.
Shiue, C Y, Salvadori, P A, Wolf, A P, Fowler, J S, & MacGregor, R R. Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose. United States.
Shiue, C Y, Salvadori, P A, Wolf, A P, Fowler, J S, and MacGregor, R R. . "Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose". United States.
@article{osti_5446138,
title = {Process for the production of /sup 18/F-2-deoxy-2-fluoro-d-glucose},
author = {Shiue, C Y and Salvadori, P A and Wolf, A P and Fowler, J S and MacGregor, R R},
abstractNote = {Process is given for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding /sup 18/F-compound by the reaction of acetyl hypofluorite or the corresponding /sup 18/F-compound with 3,4,6-tri-0-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {},
month = {}
}