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The Effect of D20 on Survival of Mice with Ascites Tumor

Technical Report ·
DOI:https://doi.org/10.2172/915075· OSTI ID:915075

The effect of deuterium oxide (D{sub 2}O) on the survival of mice inoculated with Ehrlich's mouse ascites tumor has been studied. Mice maintained on 25% and 30% D{sub 2}O drinking water showed an improved survival time of about 6 days whereas 40% D{sub 2}O drinking water had no effect on survival time. The effect is interpreted in terms of inhibition of tumor cell division and systemic toxicity.

Research Organization:
Ernest Orlando Lawrence Berkeley NationalLaboratory, Berkeley, CA (US)
Sponsoring Organization:
USAEC
DOE Contract Number:
AC02-05CH11231
OSTI ID:
915075
Report Number(s):
UCRL--3852
Country of Publication:
United States
Language:
English