Biomimetic Hydrogel Materials

Biomimetic Hydrogel Materials

Patent · Tue Apr 22 00:00:00 EDT 2003

OSTI ID:879652

Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

DOE Contract Number:: AC03-76SF00098

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: US 6552103

Application Number:: 09/574938

OSTI ID:: 879652

Country of Publication:: United States

Language:: English

References (9)

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Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors Manning, David D.; Hu, Xin; Beck, Pamela Journal of the American Chemical Society, Vol. 119, Issue 13 https://doi.org/10.1021/ja964046x	journal	April 1997
Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption Miyata, Takashi; Ootsuki, Norihito; Nakamae, Katsuhiko Macromolecular Chemistry and Physics, Vol. 195, Issue 11 https://doi.org/10.1002/macp.1994.021951107	journal	November 1994
On the wettability of poly(2-hydroxyethylmethacrylate) Morra, M.; Occhiello, E.; Garbassi, F. Journal of Colloid and Interface Science, Vol. 149, Issue 1 https://doi.org/10.1016/0021-9797(92)90393-Z	journal	March 1992
Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates Gamian, Andrzej; Chomik, Maria; Laferrière, Craig A. Canadian Journal of Microbiology, Vol. 37, Issue 3 https://doi.org/10.1139/m91-035	journal	March 1991
Poly(vinylsaccharide)s, 2 Synthesis of some poly(vinylsaccharide)s of the amide type and investigation of their solution properties Klein, Joachim; Herzog, Dieter Die Makromolekulare Chemie, Vol. 188, Issue 6, p. 1217-1232 https://doi.org/10.1002/macp.1987.021880601	journal	June 1987
Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin. Weisz, O. A.; Schnaar, R. L. Journal of Cell Biology, Vol. 115, Issue 2 https://doi.org/10.1083/jcb.115.2.485	journal	October 1991
Specific targeting of the antiviral drug 5-Iodo 2′-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine Biessen, Erik A. L.; Beuting, Diana M.; Vietsch, Helene Journal of Hepatology, Vol. 21, Issue 5 https://doi.org/10.1016/S0168-8278(94)80243-2	journal	January 1994
New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside) Roy, Rene; Tropper, Francois D.; Romanowska, Anna Bioconjugate Chemistry, Vol. 3, Issue 3 https://doi.org/10.1021/bc00015a009	journal	May 1992

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