skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Biomimetic Hydrogel Materials

Abstract

Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.

Inventors:
 [1]
  1. (Albany, CA), Mukkamala, Ravindranath (Houston, TX), Chen, Oing (Albany, CA), Hu, Hopin (Albuquerque, NM), Baude, Dominique (Creteil, FR)
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
879652
Patent Number(s):
US 6552103
Application Number:
09/574938
Assignee:
The Regents of the University of California (Oakland, CA) LBNL
DOE Contract Number:
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Bertozzi, Carolyn. Biomimetic Hydrogel Materials. United States: N. p., 2003. Web.
Bertozzi, Carolyn. Biomimetic Hydrogel Materials. United States.
Bertozzi, Carolyn. 2003. "Biomimetic Hydrogel Materials". United States. doi:. https://www.osti.gov/servlets/purl/879652.
@article{osti_879652,
title = {Biomimetic Hydrogel Materials},
author = {Bertozzi, Carolyn},
abstractNote = {Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = 2003,
month = 4
}

Patent:

Save / Share:
  • Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.
  • This patent describes a method of contrasting a proton NMR tomograph of the gastro-intestinal tract, or a portion thereof, by administering enterally to a mammal an effective image contrasting amount of a physiologically tolerable, synthetic, substantially nondegradable cross-linked hydrogel having, in the aqueous swollen state, spin-lattice or spin-spin relaxation values substantially shorter than the surrounding gastro-intestinal tissue environment; and subjecting the mammal to the proton NMR tomography.
  • A composite having a flexible hydrogel polymer formed by mixing an organic phase with an inorganic composition, the organic phase selected from the group consisting of a hydrogel monomer, a crosslinker, a radical initiator, and/or a solvent. A polymerization mixture is formed and polymerized into a desired shape and size.
  • The invention provides a method for the insertion of protein in storage vehicles and the recovery of the proteins from the vehicles, the method comprising supplying isolated protein; mixing the isolated protein with a fluid so as to form a mixture, the fluid comprising saturated phospholipids, lipopolymers, and a surfactant; cycling the mixture between a first temperature and a second temperature; maintaining the mixture as a solid for an indefinite period of time; diluting the mixture in detergent buffer so as to disrupt the composition of the mixture, and diluting to disrupt the fluid in its low viscosity state formore » removal of the guest molecules by, for example, dialysis, filtering or chromatography dialyzing/filtering the emulsified solid.« less
  • A method for removing impurities from hydrocarbon oil comprises treating the oil under refining conditions with hydrochloric acid and a calcined mixture of a silica hydrogel and a heavy metal hydrogel.