Some practical aspects of preparing polymeric hydrogels via. gamma. -irradiation

Journal Article · Fri Jul 01 04:00:00 EDT 1983 · J. Appl. Polym. Sci.; (United States)

DOI:https://doi.org/10.1002/app.1983.070280729· OSTI ID:5341187

Huglin, M B; Zakaria, M B

A considerable literature covers the preparation and properties of hydrogels for biomedical applications. The failure to emphasize practical problems in these reports should not be taken to imply, however, that such difficulties are absent. The preparative techniques usually involve polymerization or copolymerization in the presence of a crosslinking agent. Bulk polymerization is often used, or, alternatively, reaction in an aqueous medium if the monomers are fairly soluble in water. The present authors are currently studying copolymers made from a very hydrophilic vinyl lactam, a hydrophobic alkyl acrylate, and a hexafunctional methacrylate. The desired properties of the hydrophilic product include (a) optical and textural homogeneity, (b) minimal content of residual monomers and (c) ease of machinability. Bulk copolymerizaton in vacuo at 21/sup 0/C initiated by ..gamma..-irradiation from a /sup 60/Co source is employed. Resolution of certain experimental problems, which arose in this work, should be of interest to others in the field, and this constitutes the theme of the present communication.

• Research Organization: Univ. of Salford, England
• OSTI ID: 5341187
• Journal Information: J. Appl. Polym. Sci.; (United States), Journal Name: J. Appl. Polym. Sci.; (United States) Vol. 28:7; ISSN JAPNA
• Country of Publication: United States
• Language: English

Related Subjects

36 MATERIALS SCIENCE
360401* -- Polymers & Plastics-- Preparation & Fabrication-- (-1987)
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400600 -- Radiation Chemistry
ACRYLATES
ACRYLIC ACID ESTERS
AMIDES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOXYLIC ACID ESTERS
CARBOXYLIC ACID SALTS
CHEMICAL PREPARATION
CHEMICAL RADIATION EFFECTS
CHEMICAL REACTIONS
CHEMISTRY
COBALT 60
COBALT ISOTOPES
COLLOIDS
COPOLYMERIZATION
COPOLYMERS
DISPERSIONS
ELECTROMAGNETIC RADIATION
ESTERS
GAMMA RADIATION
GELS
HYDROPHYLIC POLYMERS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LACTAMS
METHACRYLIC ACID ESTERS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC POLYMERS
POLYMERIZATION
POLYMERS
RADIATION CHEMISTRY
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
SYNTHESIS
USES
YEARS LIVING RADIOISOTOPES