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Biomimetic hydrogel materials

Patent ·
OSTI ID:873177
 [1];  [2];  [1];  [3];  [4]
  1. Albany, CA
  2. Houston, TX
  3. Albuquerque, NM
  4. Creteil, FR
+ Show Author Affiliations

Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
DOE Contract Number:
AC03-76SF00098
Assignee:
Regents of University of California (Oakland, CA)
Patent Number(s):
US 6107365
OSTI ID:
873177
Country of Publication:
United States
Language:
English

References (8)

Synthetic polymeric sialoside inhibitors of influenza virus receptor-binding activity journal October 1990
Synthesis of Sulfated Neoglycopolymers:  Selective P-Selectin Inhibitors journal April 1997
Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption journal November 1994
On the wettability of poly(2-hydroxyethylmethacrylate) journal March 1992
Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates journal March 1991
Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin. journal October 1991
Specific targeting of the antiviral drug 5-Iodo 2′-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine journal January 1994
New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside) journal May 1992

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Related Subjects

/523/524/526/
99
acrylamide
acrylamide-functionalized
acrylate
biomedical
biomimetic
biomimetic hydrogel
carbohydrate
concentration
consisting
contact
containing
copolymerized
copolymerizing
derivative
fabrication
hydrogel
hydrogel materials
hydrogels
hydrophilic
hydrophobic
implants
lenses
material
material selected
materials
methacrylamide
methacrylate
method
methods
novel
preparation
selected
soft
sulfide
sulfone
sulfoxide
vinyl
wt