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Title: 1-deoxy-D-xylulose-5-phosphate reductoisomerases, and methods of use

Patent ·
OSTI ID:874583
 [1];  [1]
  1. Pullman, WA
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The present invention relates to isolated DNA sequences which code for the expression of plant 1-deoxy-D-xylulose-5-phosphate reductoisomerase protein, such as the sequence presented in SEQ ID NO:1 which encodes a 1-deoxy-D-xylulose-5-phosphate reductoisomerase protein from peppermint (Mentha x piperita). Additionally, the present invention relates to isolated plant 1-deoxy-D-xylulose-5-phosphate reductoisomerase protein. In other aspects, the present invention is directed to replicable recombinant cloning vehicles comprising a nucleic acid sequence which codes for a plant 1-deoxy-D-xylulose-5-phosphate reductoisomerase, to modified host cells transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence of the invention.

Research Organization:
Washington State University Research Foundation (Pullman, WA)
DOE Contract Number:
FG03-96ER20212
Assignee:
Washington State University Research Foundation (Pullman, WA)
Patent Number(s):
US 6420159
Application Number:
09/874562
OSTI ID:
874583
Country of Publication:
United States
Language:
English

References (7)

A General Method for the Isolation of rna Complementary to dna journal August 1962
A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis journal August 1998
Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis journal October 1998
Isoprenoid Biosynthesis via a Mevalonate-Independent Pathway in Plants: Cloning and Heterologous Expression of 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase from Peppermint journal May 1999
Reduction in the rate of DNA reassociation by sequence divergence journal December 1973
Direct formation of 2-C-methyl-d-erythritol 4-phosphate from 1-deoxy-d-xylulose 5-phosphate by 1-deoxy-d-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate journal June 1998
Cloning and heterologous expression of a cDNA encoding 1-deoxy- D -xylulose-5-phosphate reductoisomerase of Arabidopsis thaliana 1 journal July 1999

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Related Subjects

1-deoxy-d-xylulose-5-phosphate
reductoisomerases
methods
relates
isolated
dna
sequences
code
expression
plant
reductoisomerase
protein
sequence
seq
no1
encodes
peppermint
mentha
piperita
additionally
aspects
directed
replicable
recombinant
cloning
vehicles
comprising
nucleic
acid
codes
modified
host
cells
transformed
transfected
infected
andor
injected
vehicle
nucleic acid
acid sequence
cloning vehicle
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