Integrated multiplexed capillary electrophoresis system
Patent
·
OSTI ID:874423
- Ames, IA
The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.
- Research Organization:
- Ames Laboratory (AMES), Ames, IA; Iowa State University, Ames, IA (US)
- DOE Contract Number:
- W-7405-ENG-82
- Assignee:
- Iowa State University Research Foundation, Inc. (Ames, IA)
- Patent Number(s):
- US 6387234
- Application Number:
- 09/144,170
- OSTI ID:
- 874423
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
/204/422/
analysis
analytes
automates
capable
capillaries
capillary
chromatographic
columns
components
computer
computer control
controlled
denaturation
detection
detector
electrophoresis
eluting
employing
employs
fashion
flow
fluid
fluid flow
freezethaw
injection
integrated
integrates
manage
methods
movement
multiple
multiplexed
parallel
pre-concentration
processing
provided
provides
purification
reaction
sample
samples
separation
valves
analysis
analytes
automates
capable
capillaries
capillary
chromatographic
columns
components
computer
computer control
controlled
denaturation
detection
detector
electrophoresis
eluting
employing
employs
fashion
flow
fluid
fluid flow
freezethaw
injection
integrated
integrates
manage
methods
movement
multiple
multiplexed
parallel
pre-concentration
processing
provided
provides
purification
reaction
sample
samples
separation
valves