Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
Patent
·
OSTI ID:872867
- San Ramon, CA
- Tracy, CA
- Walnut Creek, CA
A method for detecting and isolating a target sequence in a sample of nucleic acids is provided using a bifunctional hybridization probe capable of hybridizing to the target sequence that includes a detectable marker and a first complexing agent capable of forming a binding pair with a second complexing agent. A kit is also provided for detecting a target sequence in a sample of nucleic acids using a bifunctional hybridization probe according to this method.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA
- DOE Contract Number:
- W-7405-ENG-48
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Number(s):
- US 6027879
- OSTI ID:
- 872867
- Country of Publication:
- United States
- Language:
- English
Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.
|
journal | November 1981 |
Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds
|
journal | May 1988 |
Gene mapping and gene enrichment by the avidin-biotin interaction: use of cytochrome-c as a polyamine bridge
|
journal | January 1978 |
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Related Subjects
/435/999/
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acid
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capable
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detectable
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nucleic
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pair
probe
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provided
sample
sequence
sequences
target
target sequence