Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
Patent
·
OSTI ID:20015509
A method for detecting and isolating a target sequence in a sample of nucleic acids is provided using a bifunctional hybridization probe capable of hybridizing to the target sequence that includes a detectable marker and a first complexing agent capable of forming a binding pair with a second complexing agent. A kit is also provided for detecting a target sequence in a sample of nucleic acids using a bifunctional hybridization probe according to this method.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA
- Sponsoring Organization:
- US Department of Energy
- DOE Contract Number:
- W-7405-ENG-48
- Assignee:
- LLNL; EDB-00:011773
- Patent Number(s):
- NONE
- Application Number:
- Int. Cl. C12Q 1/68; US 6,027,879/A/; 8-513,160
- OSTI ID:
- 20015509
- Country of Publication:
- United States
- Language:
- English
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