Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Ion-induced nuclear radiotherapy

Patent ·
OSTI ID:870567
 [1];  [1]
  1. Albuquerque, NM
+ Show Author Affiliations

Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue.

Research Organization:
AT & T CORP
DOE Contract Number:
AC04-76DP00789
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Number(s):
US 5547454
OSTI ID:
870567
Country of Publication:
United States
Language:
English

References (6)

Stereotactic Bragg Peak Proton Beam Therapy book January 1988
Charged-particle stereotactic radiosurgery
  • Lyman, John T.; Fabrikant, Jacob I.; Frankel, Kenneth A.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 10-11 https://doi.org/10.1016/0168-583X(85)90181-8
journal May 1985
Measurement of the off-resonance cross section of the 6.4 MeV nuclear reaction journal July 1988
Micro-radiosurgery: a new concept for radiotherapy based upon low energy, ion-induced nuclear reactions journal June 1993
A Note on the 3He + D Nuclear-Reaction Cross Section book December 1979
Proton Beam Therapy journal June 1982

Similar Records

Ion-induced nuclear radiotherapy
Patent · Tue Aug 20 00:00:00 EDT 1996 · OSTI ID:372574
Micro-radiosurgery: A new concept for radiotherapy based upon low energy, ion-induced nuclear reactions
Conference · Mon Nov 30 23:00:00 EST 1992 · OSTI ID:10106469
Micro-radiosurgery: A new concept for radiotherapy based upon low energy, ion-induced nuclear reactions
Conference · Tue Dec 31 23:00:00 EST 1991 · OSTI ID:6852959

Related Subjects

/600/250/
arbitrarily
atomic
based
bath
beam
broad
concept
conducting
conducts
conduit-needle
control
damage
degree
delivered
diseased
diseased tissue
dose
energetic
energy
extent
fabricated
furthermore
highly
implemented
induced
inherent
inherent limitations
inrt
intended
ion-induced
ion-induced nuclear
irradiated
irradiation
limitations
limits
nuclear
nuclear radiotherapy
nuclear reaction
nuclear reactions
outside
point-source
position
pre-defined
produce
produce highly
products
radiation
radiosurgery
radiotherapy
range
reaction
reaction product
reaction products
reactions
resulting
resulting reaction
site
source
spatial
specially
struck
target
technique
tissue
topical
treatment
tube
tumor
volume