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Title: Co-factor activated recombinant adenovirus proteinases

Abstract

This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying said peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described.

Inventors:
 [1];  [2]
  1. (Stony Brook, NY)
  2. (Shoreham, NY)
Publication Date:
Research Org.:
ASSOC UNIVERSITIES INC
OSTI Identifier:
870544
Patent Number(s):
US 5543264
Application Number:
US patent applicaiton 08/155,171
Assignee:
Associated Universities, Inc. (Washington, DC) BNL
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
co-factor; activated; recombinant; adenovirus; proteinases; application; describes; methods; expression; constructs; producing; activatable; purified; purification; described; obtaining; included; isolated; peptide; cofactors; proteinase; activity; purifying; identifying; antibodies; immunoreactive; immunospecific; preparing; related; materials; related method; recombinant adenovirus; application describes; adenovirus proteinases; related methods; antibodies immunoreactive; isolated peptide; expression constructs; activatable recombinant; purified activatable; describes methods; producing activatable; activated recombinant; adenovirus proteinase; /435/999/

Citation Formats

Anderson, Carl W., and Mangel, Walter F. Co-factor activated recombinant adenovirus proteinases. United States: N. p., 1996. Web.
Anderson, Carl W., & Mangel, Walter F. Co-factor activated recombinant adenovirus proteinases. United States.
Anderson, Carl W., and Mangel, Walter F. Tue . "Co-factor activated recombinant adenovirus proteinases". United States. https://www.osti.gov/servlets/purl/870544.
@article{osti_870544,
title = {Co-factor activated recombinant adenovirus proteinases},
author = {Anderson, Carl W. and Mangel, Walter F.},
abstractNote = {This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying said peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {8}
}

Patent:

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