No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

Ding, Yu-Shin; Fowler, Joanna S; Wolf, Alfred P

No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

Patent · Fri Jan 01 04:00:00 EST 1993

OSTI ID:868971

Ding, Yu-Shin ^[1]; Fowler, Joanna S ^[2]; Wolf, Alfred P ^[3]

Central Islip, NY
Bellport, NY
Setauket, NY

A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

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Research Organization:: ASSOC UNIVERSITIES INC

DOE Contract Number:: AC02-76CH00016

Assignee:: United States of America as represented by Department of Energy (Washington, DC)

Patent Number(s):: US 5254726

OSTI ID:: 868971

Country of Publication:: United States

Language:: English

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No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

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