No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings
Patent
·
OSTI ID:868971
- Central Islip, NY
- Bellport, NY
- Setauket, NY
A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.
- Research Organization:
- Associated Universities, Inc., Upton, NY (United States)
- DOE Contract Number:
- AC02-76CH00016
- Assignee:
- United States of America as represented by Department of Energy (Washington, DC)
- Patent Number(s):
- US 5254726
- OSTI ID:
- 868971
- Country of Publication:
- United States
- Language:
- English
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· J. Nucl. Med.; (United States)
·
OSTI ID:868971
Related Subjects
no-carrier-added
nca
aryl
18e
fluorides
via
nucleophilic
aromatic
substitution
electron
rich
rings
method
synthesizing
18
fluoride
substituted
aldehyde
compositions
bearing
donating
described
step
reacting
nitro
aldehydes
suitably
protected
hydroxyl
substitutent
reaction
government
rights
pursuant
contract
de-ac02-76ch00016
department
energy
associated
universities
associated universities
substituted aromatic
aromatic rings
/999/
nca
aryl
18e
fluorides
via
nucleophilic
aromatic
substitution
electron
rich
rings
method
synthesizing
18
fluoride
substituted
aldehyde
compositions
bearing
donating
described
step
reacting
nitro
aldehydes
suitably
protected
hydroxyl
substitutent
reaction
government
rights
pursuant
contract
de-ac02-76ch00016
department
energy
associated
universities
associated universities
substituted aromatic
aromatic rings
/999/