No-carrier-added (NCA) aryl ([sup 18]F) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

Patent · Tue Oct 19 00:00:00 EDT 1993

OSTI ID:5302745

Ding, Yushin; Fowler, J S; Wolf, A P

A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

• DOE Contract Number: AC02-76CH00016
• Assignee: Dept. of Energy, Washington, DC (United States)
• Patent Number(s): US 5254726; A
• Application Number: PPN: US 7-711684
• OSTI ID: 5302745
• Resource Relation: Patent File Date: 7 Jun 1991
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ALDEHYDES
CHEMICAL PREPARATION
FLUORIDES
ELECTRON TRANSFER
FLUORINE 18
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
FLUORINE COMPOUNDS
FLUORINE ISOTOPES
HALIDES
HALOGEN COMPOUNDS
HOURS LIVING RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
NANOSEC LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
RADIOISOTOPES
SYNTHESIS
400201* - Chemical & Physicochemical Properties