Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer

Patent · Fri Jan 01 04:00:00 EST 1988

OSTI ID:866572

Burtis, Carl A ^[1]; Johnson, Wayne F ^[2]; Walker, William A ^[3]

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1. Oak Ridge, TN
2. Loudon, TN
3. Knoxville, TN

A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises (1) a whole blood sample disc, (2) a serum sample disc, (3) a sample preparation rotor, and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc in capillary tubes filled by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analytical rotor for analysis by conventional methods.

• Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 4740472
• OSTI ID: 866572
• Country of Publication: United States
• Language: English

Related Subjects

/436/210/422/494/
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