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Title: Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer

Abstract

A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises: (1) a whole blood sample disc; (2) a serum sample disc; (3) a sample preparation rotor; and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analyticaly rotor for conventional methods. 5 figs.

Inventors:
; ;
Publication Date:
Research Org.:
Oak Ridge National Lab., TN (USA)
OSTI Identifier:
5578502
Application Number:
ON: DE86013684
Assignee:
Dept. of Energy TIC; ERA-11-005620; EDB-86-138384
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD CHEMISTRY; AUTOMATION; CENTRIFUGES; DESIGN; BLOOD SERUM; CONCENTRATORS; 550600* - Medicine

Citation Formats

Burtis, C.A., Johnson, W.F., and Walker, W.A. Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer. United States: N. p., 1985. Web.
Burtis, C.A., Johnson, W.F., & Walker, W.A. Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer. United States.
Burtis, C.A., Johnson, W.F., and Walker, W.A. Mon . "Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer". United States.
@article{osti_5578502,
title = {Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer},
author = {Burtis, C.A. and Johnson, W.F. and Walker, W.A.},
abstractNote = {A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises: (1) a whole blood sample disc; (2) a serum sample disc; (3) a sample preparation rotor; and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analyticaly rotor for conventional methods. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Aug 05 00:00:00 EDT 1985},
month = {Mon Aug 05 00:00:00 EDT 1985}
}