Antihypertensive neutral lipid
Patent
·
OSTI ID:865882
- Oak Ridge, TN
The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.
- Research Organization:
- OAK RIDGE ASSOC UNIV
- DOE Contract Number:
- AC05-76OR00033
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Number(s):
- US 4595681
- OSTI ID:
- 865882
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
/514/999/
acetyl
acetylated
acyl
alkyl
animals
antihypertensive
blood
blood pressure
capacity
carbon
carbon chain
chain
chain alkyl
discovery
effect
ether-linked
glycerolipids
hydroxyl
lipid
neutral
physiological
position
pressure
propionyl
relates
requiring
sensitive
sn-1
sn-2
sn-3
structure
warm-blooded
warm-blooded animals
acetyl
acetylated
acyl
alkyl
animals
antihypertensive
blood
blood pressure
capacity
carbon
carbon chain
chain
chain alkyl
discovery
effect
ether-linked
glycerolipids
hydroxyl
lipid
neutral
physiological
position
pressure
propionyl
relates
requiring
sensitive
sn-1
sn-2
sn-3
structure
warm-blooded
warm-blooded animals