Antihypertensive neutral lipid
A method is described for treating a warm-blooded animal comprising administering to the animal a neutral glycerolipid with a 12 to 20 carbon alkyl group at the sn-1 position, a short carbon chain acyl group at the sn-2 position and a hydroxyl group at the sn-3 position in an amount sufficient to lower the arterial blood pressure of the animal. A method is also described for treating a warm-blooded animal comprising administering a composition consisting essentially of a 1-alkyl-2-acetyl (or propionyl)-sn glycerol in combination with a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, wherein the 1-alkyl groups contain 12 to 20 carbon atoms, dissolved in an inert pharmaceutically acceptable solvent in amounts sufficient to lower the arterial blood pressure of the animal.
- Assignee:
- Dept. of Energy, Washington, DC
- Patent Number(s):
- US 4595681
- OSTI ID:
- 5578512
- Country of Publication:
- United States
- Language:
- English
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Antihypertensive neutral lipid
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIHYPERTENSIVE AGENTS
BLOOD PRESSURE
CARBON
CARDIOVASCULAR AGENTS
CARDIOVASCULAR DISEASES
DISEASES
DISSOLUTION
DRUGS
ELEMENTS
HYPERTENSION
LIPIDS
NONMETALS
ORGANIC COMPOUNDS
QUANTITY RATIO
SYMPTOMS
THERAPEUTIC USES
THERAPY
USES
VASCULAR DISEASES