Antihypertensive neutral lipid
Patent
·
OSTI ID:5847534
The invention relates to the discovery of a class of neutral acetylated either-linked glycerolipids having the capacity to lower blood presure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.
- DOE Contract Number:
- AC05-76OR00033
- Assignee:
- Dept. of Energy
- Application Number:
- ON: DE85011625
- OSTI ID:
- 5847534
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LIPIDS
BIOLOGICAL EFFECTS
CHEMICAL PREPARATION
BLOOD PRESSURE
MAMMALS
ANIMALS
ORGANIC COMPOUNDS
SYNTHESIS
VERTEBRATES
400301* - Organic Chemistry- Chemical & Physicochemical Properties- (-1987)
560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LIPIDS
BIOLOGICAL EFFECTS
CHEMICAL PREPARATION
BLOOD PRESSURE
MAMMALS
ANIMALS
ORGANIC COMPOUNDS
SYNTHESIS
VERTEBRATES
400301* - Organic Chemistry- Chemical & Physicochemical Properties- (-1987)
560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)