X-ray stereotactic lesion localization in conjunction with dedicated scintimammography

Journal Article · Wed Oct 01 04:00:00 EDT 2003 · IEEE Transactions on Nuclear Science

OSTI ID:834841

More, Mitali J; Narayanan, Deepa; Goodale, Patricia J; Majewski, Stanislaw; Welch, Benjamin; Wojcik, Randolph; Williams, Mark

We are developing a dual modality system that combines digital X-ray mammography with gamma emission scintigraphy on an upright mammography gantry. The breast is held under mild compression by a support structure that is independent of the detectors. The X-ray source and detectors can be rotated around a fixed rotation axis permitting multiple views of the breast with fixed compression. Two such views can be combined as a stereotactic pair to obtain the three-dimensional location of breast lesions. Information about the location of the lesion within the breast permits corrections for attenuation and detector spatial resolution, resulting in more accurate estimation of the true lesion-to-background concentration ratio, based on the image lesion-to-background counts ratio. In this paper, we describe the model used to make these corrections, and present the results of the phantom experiments designed to test the accuracy of our calculations.

• Research Organization: Thomas Jefferson National Accelerator Facility, Newport News, VA (US)
• Sponsoring Organization: USDOE Office of Energy Research (ER) (US)
• DOE Contract Number: AC05-84ER40150
• OSTI ID: 834841
• Report Number(s): JLAB-PHY-03-59; DOE/ER/40150-3004
• Journal Information: IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 5 Vol. 50; ISSN 0018-9499; ISSN IETNAE
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
ACCURACY
ATTENUATION
GAMMA RADIATION
MAMMARY GLANDS
PHANTOMS
SCINTISCANNING
SPATIAL RESOLUTION
X-RAY SOURCES