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Title: X-ray stereotactic lesion localization in conjunction with dedicated scintimammography

Abstract

We are developing a dual modality system that combines digital X-ray mammography with gamma emission scintigraphy on an upright mammography gantry. The breast is held under mild compression by a support structure that is independent of the detectors. The X-ray source and detectors can be rotated around a fixed rotation axis permitting multiple views of the breast with fixed compression. Two such views can be combined as a stereotactic pair to obtain the three-dimensional location of breast lesions. Information about the location of the lesion within the breast permits corrections for attenuation and detector spatial resolution, resulting in more accurate estimation of the true lesion-to-background concentration ratio, based on the image lesion-to-background counts ratio. In this paper, we describe the model used to make these corrections, and present the results of the phantom experiments designed to test the accuracy of our calculations.

Authors:
; ; ; ; ; ;
Publication Date:
Research Org.:
Thomas Jefferson National Accelerator Facility, Newport News, VA (US)
Sponsoring Org.:
USDOE Office of Energy Research (ER) (US)
OSTI Identifier:
834841
Report Number(s):
JLAB-PHY-03-59; DOE/ER/40150-3004
Journal ID: ISSN 0018-9499; IETNAE; TRN: US0407324
DOE Contract Number:  
AC05-84ER40150
Resource Type:
Journal Article
Journal Name:
IEEE Transactions on Nuclear Science
Additional Journal Information:
Journal Volume: 50; Journal Issue: 5; Other Information: IEEE Transactions on Nuclear Science, Volume 50, Issue 5, Page(s) 1636 - 1642; PBD: 1 Oct 2003; Journal ID: ISSN 0018-9499
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ACCURACY; ATTENUATION; MAMMARY GLANDS; PHANTOMS; SCINTISCANNING; SPATIAL RESOLUTION; X-RAY SOURCES; GAMMA RADIATION

Citation Formats

Mitali J. More, Deepa Narayanan, Patricia J. Goodale, Stanislaw Majewski, Benjamin Welch, Randolph Wojcik, and Mark Williams. X-ray stereotactic lesion localization in conjunction with dedicated scintimammography. United States: N. p., 2003. Web.
Mitali J. More, Deepa Narayanan, Patricia J. Goodale, Stanislaw Majewski, Benjamin Welch, Randolph Wojcik, & Mark Williams. X-ray stereotactic lesion localization in conjunction with dedicated scintimammography. United States.
Mitali J. More, Deepa Narayanan, Patricia J. Goodale, Stanislaw Majewski, Benjamin Welch, Randolph Wojcik, and Mark Williams. Wed . "X-ray stereotactic lesion localization in conjunction with dedicated scintimammography". United States. https://www.osti.gov/servlets/purl/834841.
@article{osti_834841,
title = {X-ray stereotactic lesion localization in conjunction with dedicated scintimammography},
author = {Mitali J. More and Deepa Narayanan and Patricia J. Goodale and Stanislaw Majewski and Benjamin Welch and Randolph Wojcik and Mark Williams},
abstractNote = {We are developing a dual modality system that combines digital X-ray mammography with gamma emission scintigraphy on an upright mammography gantry. The breast is held under mild compression by a support structure that is independent of the detectors. The X-ray source and detectors can be rotated around a fixed rotation axis permitting multiple views of the breast with fixed compression. Two such views can be combined as a stereotactic pair to obtain the three-dimensional location of breast lesions. Information about the location of the lesion within the breast permits corrections for attenuation and detector spatial resolution, resulting in more accurate estimation of the true lesion-to-background concentration ratio, based on the image lesion-to-background counts ratio. In this paper, we describe the model used to make these corrections, and present the results of the phantom experiments designed to test the accuracy of our calculations.},
doi = {},
journal = {IEEE Transactions on Nuclear Science},
issn = {0018-9499},
number = 5,
volume = 50,
place = {United States},
year = {2003},
month = {10}
}