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Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system

Patent ·
OSTI ID:1069109
 [1];  [2];  [3]
  1. Seattle, WA
  2. Morgantown, WV
  3. Hampton, VA
+ Show Author Affiliations

An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.

Research Organization:
Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-84ER40150
Assignee:
Jefferson Science Associates, LLC (Newport News, VA)
Patent Number(s):
RE43,499
Application Number:
12/913,372
OSTI ID:
1069109
Country of Publication:
United States
Language:
English

References (3)

Optimization of breast imaging procedure with dedicated compact gamma cameras
  • Kieper, D.; Majewski, S.; Kross, B.
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 497, Issue 1 https://doi.org/10.1016/S0168-9002(02)01907-1
journal January 2003
Optimization of dedicated scintimammography procedure using detector prototypes and compressible phantoms journal June 2001
Improved lesion visibility in a dedicated dual head scintimammography system - phantom results conference January 2003

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Related Subjects

60 APPLIED LIFE SCIENCES