Environmental determinants of human cancer. [Hydrocarbons, Pesticides, Coal, Dyes, Rubber]

Journal Article · Tue Oct 01 04:00:00 EDT 1974 · Cancer Res.; (United States)

OSTI ID:7349144

Epstein, S S

Environmental determinants of human cancer are reviewed, with particular emphasis on chemical carcinogens. Topics covered include: the prevalence of human cancer, categorization of chemical carcinogens, quantitative and qualitative extrapolation from toxicological data, the alleged distinctions between species-specific carcinogens and between tumorigens and carcinogens, general epidemiological considerations, and an evaluation of the benefit-risk calculus. Chemicals of suspected or known carcinogenicity include: chlorinated hydrocarbon pesticides such as aldrin, dieldrin, and dichlorodiphenyltrichloroethane; polynuclear compounds such as benzo(a)pyrene and benzo(a)anthracene; bis(chloromethyl) ether; 2-naphthylamine; benzidine; 2-aminobiphenyl; 2-nitrobiphenyl; estrogens; and carbon tetrachloride. Occupational situations reported in connection with cancer incidence include: working with chimney soot, dye and rubber manufacturing, coal and metal mining, asbestos handling, and polyvinyl chloride manufacturing. (Air Pollut. Abstr.)

• OSTI ID: 7349144
• Journal Information: Cancer Res.; (United States), Journal Name: Cancer Res.; (United States) Vol. 34:10; ISSN CNREA
• Country of Publication: United States
• Language: English

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54 ENVIRONMENTAL SCIENCES
AIR POLLUTION
AMINES
ANIMALS
AROMATICS
ASBESTOS
BENZANTHRACENE
BENZIDINE
BENZOPYRENE
CARBON TETRACHLORIDE
CARBONACEOUS MATERIALS
CARCINOGENS
CHLORINATED ALIPHATIC HYDROCARBONS
COAL
CONDENSED AROMATICS
DISEASES
DYES
ELASTOMERS
ENERGY SOURCES
ENVIRONMENTAL EFFECTS
EPIDEMIOLOGY
ESTROGENS
FOSSIL FUELS
FUELS
HALOGENATED ALIPHATIC HYDROCARBONS
HORMONES
HYDROCARBONS
MAMMALS
MAN
MINING
NEOPLASMS
OCCUPATIONS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC POLYMERS
PESTICIDES
POLLUTION
POLYMERS
PRIMATES
RUBBERS
STEROID HORMONES
VERTEBRATES
WORKING CONDITIONS