Mortality of workers employed at organochlorine pesticide manufacturing plants: An update

Technical Report · Mon Jul 01 00:00:00 EDT 1991

OSTI ID:6692855

Brown, D P

A mortality study of workers at four organochlorine pesticide manufacturing factories was updated through 1987. The cohorts included all white male workers employed for at least 6 months before December 31, 1964 at the four factories. The workers had been exposed to the following organochlorine pesticides: chlordane, heptachlor, endrin, aldrin, dieldrin, and dichlorodiphenyltrichloroethane (DDT). Workers at one factory had been exposed to the organobromine pesticide dibromochloropropane. The total number of deaths for the period from 1976 through 1987 was 650. Mortality for all causes and all malignant neoplasms was lower than expected at each of the factories. Cerebrovascular disease mortality was elevated for three of the four factories. The most important result was the statistically significant increase in liver/biliary tract cancer among workers at the facility where aldrin and dieldrin were the primary organochlorine pesticides produced and the nonsignificant increase at the facility where DDT was manufactured.

• Research Organization: National Inst. for Occupational Safety and Health, Cincinnati, OH (United States)
• OSTI ID: 6692855
• Report Number(s): PB-93-145738/XAB
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALDRIN
AROMATICS
CHLORINATED AROMATIC HYDROCARBONS
CHLORINE
DDT
DIELDRIN
DISEASES
ELEMENTS
EPIDEMIOLOGY
HALOGENATED AROMATIC HYDROCARBONS
HALOGENS
INDUSTRIAL MEDICINE
INSECTICIDES
MANUFACTURING
MEDICINE
MORTALITY
NEOPLASMS
NONMETALS
OCCUPATIONAL EXPOSURE
OCCUPATIONAL SAFETY
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
PESTICIDES
RESEARCH PROGRAMS
RISK ASSESSMENT
SAFETY
TOXICITY