Myocardial uptake of thallium-201 augmented with bicarbonate: concise communication

Journal Article · Sat Jan 01 04:00:00 EST 1977 · J. Nucl. Med.; (United States)

OSTI ID:7334026

Hetzel, K R; Westerman, B R; Quinn, III, J L; Meyers, S; Barresi, V

Sodium bicarbonate was used to enhance the myocardial concentration of Tl-201 in rabbits and dogs. Organ distribution studies in rabbits and in vivo imaging in dogs showed a 1.5 to 2-fold increase in myocardial Tl-201 concentration in bicarbonate-treated animals as compared with matched controls. Image improvement was noted, with threefold enhancement of myocardium-to-liver ratios. The results suggest that a similar improvement may be possible for clinical myocardial imaging.

• Research Organization: Northwestern Univ., Chicago
• OSTI ID: 7334026
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 18:1; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL COMPOUNDS
ANIMALS
BETA DECAY RADIOISOTOPES
BODY
CARBON COMPOUNDS
CARBONATES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DOGS
ELECTRON CAPTURE RADIOISOTOPES
HEART
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
RABBITS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
SODIUM CARBONATES
SODIUM COMPOUNDS
THALLIUM 201
THALLIUM ISOTOPES
UPTAKE
VERTEBRATES