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Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction

Journal Article · · Circulation; (United States)
; ; ; ;

Technetium-99m stannous pyrophosphate (/sup 99m/Tc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positive (2+) scintigram. At follow-up scintigraphy 6 to 37 weeks following AMI, 57% of patients had a persistently positive scintigram even though recurrent AMI was suspected in only one of these patients. Patients with persistently positive scintigrams tended to have more severe disease as evidenced by compensated congestive heart failure (41%), persistent angina (77%), and ECG evidence of ventricular dyssynergy (51%). We conclude that (1) in patients with prior AMI, a 2+ abnormality on /sup 99m/Tc-PYP scintigrams may not represent new AMI;2) a persistently positive /sup 99m/Tc-PYP scintigram may have prognostic implications since it occurs predominantly in patients with severe symptomatic coronary disease.

Research Organization:
Univ. of California, Irvine
OSTI ID:
7323960
Journal Information:
Circulation; (United States), Journal Name: Circulation; (United States) Vol. 56:2; ISSN CIRCA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PATIENTS
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES