Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Technetium stannous pyrophosphate myocardial scintigrams in the recognition of myocardial infarction in patients undergoing coronary artery revascularization

Journal Article · · Ann. Thorac. Surg.; (United States)

Myocardial imaging using technetium 99m stannous pyrophosphate (/sup 99m/Tc-PYP) has been utilized preoperatively and three to five days postoperatively to detect myocardial infarction in 48 patients undergoing aortocoronary bypass grafting, including 7 having valve replacement (5 aortic, 2 mitral) in addition to revascularization. In the total group of patients operated on there were 3 deaths (6%). Preoperatively, 26 patients had unstable angina and 10 had severe left main coronary artery disease. Eleven of the 48 (23%) were women. ECG and enzyme-proved infarctions occurred in 6 of the 48 patients (12%), but the addition of /sup 99m/Tc-PYP myocardial imaging demonstrated scintigraphic evidence of infarction in 15 patients (31%), including 2 who died in the operating room. The /sup 99m/Tc-PYP myocardial imaging technique, which has proved safe, simple, and relatively inexpensive in these patients, suggests that the incidence of infarction after coronary bypass operations is somewhat higher than has been previously recognized from just ECG and enzyme changes. This technique also has been of value in helping to exclude myocardial infarction in difficult clinical situations such as postoperative arrhythmias and the postpericardiotomy syndrome.

Research Organization:
Univ. of Texas, Dallas
OSTI ID:
7120584
Journal Information:
Ann. Thorac. Surg.; (United States), Journal Name: Ann. Thorac. Surg.; (United States) Vol. 21:4; ISSN ATHSA
Country of Publication:
United States
Language:
English