Plasmodium berghei berghei: irradiated sporozoites of the ANKA strain as immunizing antigens in mice. [X radiation]

Journal Article · Tue Jun 01 04:00:00 EDT 1976 · Exp. Parasitol.; (United States)

DOI:https://doi.org/10.1016/0014-4894(76)90048-5· OSTI ID:7322870

Beaudoin, R L; Strome, C P.A.; Tubergen, T A; Mitchell, F

Mice were protected against challenge with infective sporozoites following immunization with x-ray irradiated sporozoites. The immunity lasted at least 8 weeks. Mice immune against sporozoite challenge remained fully susceptible to challenge with erythrocytic stages. Immunization of mice with extracts of mosquito thorax failed to protect them, indicating that mosquito antigens were not directly responsible for the immunity observed in the basic experiments.

• Research Organization: Naval Medical Research Inst., Bethesda, MD
• OSTI ID: 7322870
• Journal Information: Exp. Parasitol.; (United States), Journal Name: Exp. Parasitol.; (United States) Vol. 39:3; ISSN EXPAA
• Country of Publication: United States
• Language: English

Related Subjects

560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ANTIGENS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELECTROMAGNETIC RADIATION
IMMUNITY
INVERTEBRATES
IONIZING RADIATIONS
MAMMALS
MICE
MICROORGANISMS
PARASITES
PLASMODIUM
PROTOZOA
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
X RADIATION