Genetic damage induced by occupationally low mercury exposure

Journal Article · Wed Dec 01 04:00:00 EST 1976 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(76)90040-2· OSTI ID:7310724

Verschaeve, L ^[1]; Kirsch-Volders, M; Susanne, C; Groetenbriel, C; Hausterman's, R; Lecomte, A; Roossels, D

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1. Univ., Brussels

Lymphocytes from whole blood cultures from 28 subjects occupationally exposed to different mercury compounds and from seven control subjects were studied cytogenetically. Differences between aneuploidy of exposed and nonexposed subjects were found statistically significant for all analyzed mercury compounds. No statistically significant difference however (except for ethylmercury exposure) was observed for the frequency of cells with structural chromosome aberrations although all of the observed frequencies in exposed subjects were higher than those of the controls. A significant correlation was found between the blood and urine mercury levels on the one hand and the total amount of cells with chromosomal aberrations and frequencies of cells with other than chromatid type aberrations on the other.

• OSTI ID: 7310724
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 12:3; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

550400 -- Genetics
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BIOLOGY
BLOOD
BLOOD CELLS
BODY FLUIDS
CHROMOSOMAL ABERRATIONS
CHRONIC INTAKE
CONNECTIVE TISSUE CELLS
CYTOLOGY
DISEASES
ELEMENTS
GENETIC EFFECTS
GENETICS
INTAKE
LEUKOCYTES
LYMPHOCYTES
MERCURY
METALS
MUTATIONS
OCCUPATIONAL DISEASES
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
SOMATIC CELLS
URINE
WASTES