Esterase-6 (Es-6) in laboratory mice: hormone-influenced expression and linkage relationship to oligosyndactylism (Os), Esterase-1 (Es-1), and Esterase-2 (Es-2) in chromosome 8

Journal Article · Wed Jan 01 04:00:00 EST 1975 · Biochem. Genet.; (United States)

DOI:https://doi.org/10.1007/BF00485816· OSTI ID:7299581

Womack, J E

Allelic differences at an esterase locus designated Es-6 exist between mouse strain C57BL/6J and a laboratory stock of Mus musculus molossinus. Strain C57BL/6J has been assigned the allele Es-6/sup a/ and Mus musculus molossinus the alternate allele ES-6/sup b/. Kidney expression of the electrophoretic esterase band controlled by the Es-6 locus is sex influenced, with increased activity apparently induced by testosterone. A four-point test cross established the gene order Os--Es-1--Es-6--Es-2 within a 10-cM segment on chromosome 8. (auth)

• Research Organization: Jackson Lab., Bar Harbor, ME
• OSTI ID: 7299581
• Journal Information: Biochem. Genet.; (United States), Journal Name: Biochem. Genet.; (United States) Vol. 13:5/6; ISSN BIGEB
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
550500 -- Metabolism
59 BASIC BIOLOGICAL SCIENCES
ANDROGENS
ANDROSTANES
ANIMALS
BIOCHEMISTRY
BIOLOGICAL VARIABILITY
BIOLOGY
BODY
CHEMISTRY
CHROMOSOMES
ELECTROPHORESIS
ENZYMES
ESTERASES
GENES
GENETIC VARIABILITY
GENETICS
HORMONES
HYDROLASES
HYDROXY COMPOUNDS
KETONES
KIDNEYS
MAMMALS
MICE
ORGANIC COMPOUNDS
ORGANS
RODENTS
SEX
STEROID HORMONES
STEROIDS
TESTOSTERONE
VERTEBRATES