Radioimmunoassay for norethindrone. II. Plasma levels in hypertensive and normotensive oral contraceptive users. [/sup 3/H]

Journal Article · Thu Jan 01 04:00:00 EST 1976 · Anal. Lett.; (United States)

DOI:https://doi.org/10.1080/00032717608059083· OSTI ID:7286135

Verma, P; Curry, C; Ahluwalia, B

A sensitive radioimmunoassay for measurement of norethindrone (N) in blood plasma has been developed. The coefficient of variation within the assay and between assays was 7 and 13.5 percent respectively. The procedural blanks were negligible, and recovery was approximately 81.8 percent. Blood plasma levels of N in 20 normotensive and 6 hypertensive women who were ingesting oral contraceptives (OCs) were measured, and the results indicate that the subjects who became hypertensive while taking OCs had significantly higher levels of N compared with normotensive OC users (p less than 0.001). (auth)

• Research Organization: Howard Univ., Washington, DC
• OSTI ID: 7286135
• Journal Information: Anal. Lett.; (United States), Journal Name: Anal. Lett.; (United States) Vol. 9:1; ISSN ANALB
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY FLUIDS
CARDIOVASCULAR DISEASES
DISEASES
FEMALES
IMMUNE SERUMS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
MAN
ORGANIC COMPOUNDS
PRIMATES
RADIOASSAY
RADIOIMMUNOASSAY
STEROIDS
TRACER TECHNIQUES
TRITIUM COMPOUNDS
VERTEBRATES
WOMEN