Cytogenetic damage and occupational exposure. 1. Exposure to stone dust

Journal Article · Tue Oct 01 04:00:00 EDT 1991 · Environmental Research; (United States)

DOI:https://doi.org/10.1016/S0013-9351(05)80106-9· OSTI ID:7248908

Sobti, R C; Bhardwaj, D K ^[1]

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1. Panjab Univ., Chandigarh (India)

Cytogenetic investigations were carried out on 50 workers exposed to stone dust in a stone crusher industry and on 25 control subjects never exposed to such dust. The frequency of chromosomal aberrations and sister chromatid exchanges in exposed individuals was significantly higher than that in controls. The cytogenetic indices demonstrated a clear dependence on the working environment. The effect of smoking and/or alcoholic habits coupled with exposure to stone dust has also been investigated. The results indicate that the mutagenic risk in the working environment is probably associated with silica dust in the area.

• OSTI ID: 7248908
• Journal Information: Environmental Research; (United States), Journal Name: Environmental Research; (United States) Vol. 56:1; ISSN ENVRA; ISSN 0013-9351
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
540120 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ASIA
BUILDING MATERIALS
CHALCOGENIDES
CHROMOSOMAL ABERRATIONS
DEVELOPING COUNTRIES
DUSTS
INDIA
INHALATION
INTAKE
MALES
MAMMALS
MAN
MATERIALS
MEN
MUTAGENESIS
MUTATIONS
OCCUPATIONAL EXPOSURE
OXIDES
OXYGEN COMPOUNDS
PERSONNEL
PRIMATES
SILICON COMPOUNDS
SILICON OXIDES
SISTER CHROMATID EXCHANGES
VERTEBRATES
WORKING CONDITIONS