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Reaction of alkane- and arenesulfonamides with allylic electrophiles, catalyzed by transition-metal complexes

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:7159931

The reactions of N-methyl-, N-phenyl-, N-amyl-, and N-allyl-p-toluenesulfonamides and the corresponding butanesulfonamides and also of unsubstituted p-toluenesulfonamide with allyl alcohols, ethers, esters, amines, sulfides, and sulfones, catalyzed by the low-valence compounds of palladium nickel, iron, cobalt, zirconium, chromium, and copper and leading to difficultly obtainable N-alkenylsulfonamides with specific structures, were investigated. The complex catalysts based on compounds of nickel, iron, and copper activated with triphenylphosphine direct the reaction of N-methyltoluenesulfonamide with 2,7-octadienyl acetate toward the exclusive formation of N-methyl-N-(1,7-octadiene-3-yl)-p-toluenesulfonamide, while the phosphine complexes of palladium direct the reaction toward N-methyl-N-(2,7-octadienyl)-p-toluenesulfonamide. The ..pi..-allyl complexes of palladium, containing the sulfonamide molecules in the coordination sphere of the central atom of the catalyst, promote the isomerization of 2,7-octadienyl acetate to the branched 1,7-isomer.

Research Organization:
Institute of Chemistry, Ufa (USSR)
OSTI ID:
7159931
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 23:4; ISSN JOCYA
Country of Publication:
United States
Language:
English

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