Blood lead: an inadequate measure of occupational exposure

Journal Article · Sat Mar 01 04:00:00 EDT 1975 · J. Occup. Med.; (United States)

OSTI ID:7148068

Vitale, L F; Joselow, M M; Wedeen, R P; Pawlow, M

Thirty lead workers were investigated for possible excessive lead exposure using the following screening tests: blood lead, delta-aminolevulinic acid dehydratase (ALAD), urinary delta-aminolevulinic acid (ALA), free erythrocyte protoporphyrin (FEP), urinary lead, and edathamil calcium disodium (EDTA) mobilization. It was shown that an increased body burden of lead as evidenced by the more sensitive tests can coexist with blood lead levels below 80 ..mu..g/100 ml and that workers with blood lead concentrations below this currently accepted safe level may manifest evidence of lead nephropathy. It is concluded that the blood lead concentration alone is an inadequate measure of occupational exposure.

• OSTI ID: 7148068
• Journal Information: J. Occup. Med.; (United States), Journal Name: J. Occup. Med.; (United States) Vol. 17:3; ISSN JOCMA
• Country of Publication: United States
• Language: English

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54 ENVIRONMENTAL SCIENCES
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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
AMINO ACIDS
AMINOLEVULINIC ACID
BIOASSAY
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY BURDEN
BODY FLUIDS
CARBOXYLIC ACIDS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
ENZYMES
HAZARDS
HEALTH HAZARDS
INDUSTRIAL MEDICINE
LEAD
MAXIMUM PERMISSIBLE EXPOSURE
MEDICINE
METALS
OCCUPATIONAL DISEASES
ORGANIC ACIDS
ORGANIC COMPOUNDS
PUBLIC HEALTH
SAFETY STANDARDS
STANDARDS
TOXICITY
URINE
WASTES