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Radiopharmaceuticals for diagnosis and treatment. Progress report, August 1, 1976--July 31, 1977. [/sup 125/I, /sup 131/I, /sup 75/Se, /sup 14/C, /sup 32/P]

Technical Report ·
OSTI ID:7145043

Progress is reported on the following research projects: diagnosis of adrenal cortex diseases using /sup 131/I-19-iodocholesterol, NP-59 or 6..beta..-I-131-iodo-methyl-19-norcholesterol-5(10)-enol, Se-75-19-selenocholesterol, Se-75-6..beta..-benzyl-selenomethyl-19-norcholesterol-5(10)-en-3..beta..-ol, and radiolabeled enzyme inhibitors; diagnosis of adrenal medulla diseases using radiolabeled cholesterols and enzyme inhibitors and dopamine analogs; tissue distribution of /sup 14/C-, /sup 125/I-, and /sup 131/I-diphenylhydantoin in the toadfish, rat, and human with insulinomas of the pancreas; concentration of /sup 14/C and /sup 125/I-labeled quinoline analogs in malignant melanomas of mice; calcium, phosphorus, and magnesium content of mammary cancers and normal mammary tissue of women in relation to uptake of /sup 32/P labeled bone scanning agents; and development of purified immunoglobulins with specific antibody reactivity to tumor-associated antigens, labeled with /sup 125/I or /sup 131/I. (HLW)

Research Organization:
Michigan Univ., Ann Arbor (USA)
OSTI ID:
7145043
Report Number(s):
COO-2031-4
Country of Publication:
United States
Language:
English

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