Analysis of mutagenic activity of biohazardous organics in Kanawha River sediments. Technical completion report
Technical Report
·
OSTI ID:7138370
Residual chemical contamination of Kanawha River sediments may constitute a health hazard. Sediment cores have been analyzed using a coupled bioassay/chemical fractionation procedure. Both bacterial mutagenicity and sister chromatid exchange (SCE) analyses were conducted on sediment samples. Pocatalico River sediments extracts showed no response in either bacterial mutagenicity assay or SCE assay. Extracts from Armour Creek and the Kanawha River induced mutagenicities in the presence of S9 enzymes. The same extracts produced a significant increase in human chromosomal cross-over events.
- Research Organization:
- West Virginia Univ., Morgantown, WV (USA). Water Research Inst.
- OSTI ID:
- 7138370
- Report Number(s):
- PB-90-191529/XAB
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
54 ENVIRONMENTAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DIOXIN
MUTAGEN SCREENING
POLYCYCLIC AROMATIC HYDROCARBONS
SEDIMENTS
CONTAMINATION
WEST VIRGINIA
WATER POLLUTION
METABOLIC ACTIVATION
RIVERS
SISTER CHROMATID EXCHANGES
TOXICITY
AROMATICS
CHROMOSOMAL ABERRATIONS
FEDERAL REGION III
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
MUTATIONS
NORTH AMERICA
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
POLLUTION
SCREENING
STREAMS
SURFACE WATERS
USA
540320* - Environment
Aquatic- Chemicals Monitoring & Transport- (1990-)
560300 - Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DIOXIN
MUTAGEN SCREENING
POLYCYCLIC AROMATIC HYDROCARBONS
SEDIMENTS
CONTAMINATION
WEST VIRGINIA
WATER POLLUTION
METABOLIC ACTIVATION
RIVERS
SISTER CHROMATID EXCHANGES
TOXICITY
AROMATICS
CHROMOSOMAL ABERRATIONS
FEDERAL REGION III
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
MUTATIONS
NORTH AMERICA
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
POLLUTION
SCREENING
STREAMS
SURFACE WATERS
USA
540320* - Environment
Aquatic- Chemicals Monitoring & Transport- (1990-)
560300 - Chemicals Metabolism & Toxicology