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U.S. Department of Energy
Office of Scientific and Technical Information

Effect of long-wave ultraviolet light on the lens. I. Model systems for detecting and measuring effect on the lens in vitro

Journal Article · · Invest. Ophthalmol.; (United States)
OSTI ID:7120470
Rat, mouse, and chick lenses incubated with 3-aminotriazole under long-wave ultraviolet (UV) show reduced accumulation and incorporation of leucine and a loss of glutathione. The effect on leucine incorporation is strikingly enhanced when capsule-epithelium pools are incubated. The procedure may identify photosensitizers or metabolic inhibitors which are cataractogenic when acting in conjunction with UV.
Research Organization:
Emory Univ., Atlanta
OSTI ID:
7120470
Journal Information:
Invest. Ophthalmol.; (United States), Journal Name: Invest. Ophthalmol.; (United States) Vol. 15:5; ISSN INOPA
Country of Publication:
United States
Language:
English