Clinical evaluation of direct and photosensitized ultraviolet radiation damage to the lens
Journal Article
·
· Ann. Ophthalmol.; (United States)
OSTI ID:7068975
We are reporting a new, objective, and quantitative method for monitoring age-related molecular changes in the human ocular lens in vivo, as expressed by increases in at least two (nontryptophan) fluorescence wavelengths. These fluorescence wavelengths appear to be caused by photochemically induced changes in the lens, and they reflect the ultraviolet (UV) filtering capacity of the patients' ocular lenses. These data correlate with previously reported in vitro lens fluorescence changes that are associated with the aging process. This method will also detect alterations in lenticular fluorescence caused by photosensitized as well as direct UV radiation damage.
- Research Organization:
- Klinisches Institute fur Experimentelle Ophthalmologie Der Universitat Bonn, Venusberg, West Germany
- OSTI ID:
- 7068975
- Journal Information:
- Ann. Ophthalmol.; (United States), Journal Name: Ann. Ophthalmol.; (United States) Vol. 14:3; ISSN ANOPB
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550200 -- Biochemistry
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
BIOCHEMISTRY
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMICAL REACTIONS
CHEMISTRY
CRYSTALLINE LENS
ELECTROMAGNETIC RADIATION
EYES
FACE
FLUORESCENCE
HEAD
IN VIVO
LUMINESCENCE
ORGANS
PATIENTS
PHOTOCHEMICAL REACTIONS
RADIATION EFFECTS
RADIATIONS
SENSE ORGANS
ULTRAVIOLET RADIATION
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
BIOCHEMISTRY
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMICAL REACTIONS
CHEMISTRY
CRYSTALLINE LENS
ELECTROMAGNETIC RADIATION
EYES
FACE
FLUORESCENCE
HEAD
IN VIVO
LUMINESCENCE
ORGANS
PATIENTS
PHOTOCHEMICAL REACTIONS
RADIATION EFFECTS
RADIATIONS
SENSE ORGANS
ULTRAVIOLET RADIATION