Ultraviolet-induced photochemical damage in the ocular tissues. Final report

Technical Report · Mon May 01 00:00:00 EDT 1989

OSTI ID:5401634

Zuclich, J A

Exposure to ultraviolet lasers may result in pathology to either the cornea, lens, or retina of the primate eye. The particular combination of exposure parameters (wavelength, peak power, pulsewidth, pulse repetition rate and total energy delivered) determine the target tissue(s) in each instance. The effect may be acute or chronic, and the implicated damage mechanism categorized as photochemical, photoablative or thermal. This discussion summarizes a number of specific cases where ultraviolet-laser radiation affected the cornea, lens and/or retina; will describe the nature of the pathologies; and will indicate what is known about the damage mechanisms in each case. Ranges of exposure parameters where each ocular tissue is the most sensitive will be defined. Data discussed include the action spectra for far- and near-ultraviolet induced ocular damage; the pulse width and total energy dependencies of corneal and lens thresholds; cumulative effects of repeated ultraviolet exposures and repair or recovery rates. Finally, retinal photoreceptor damage resulting from near-UV laser exposures is described. This apparent photochemical effect was observed following exposure to a 325-nm helium cadmium laser when 0.28 J was delivered to the eye.

• Research Organization: Krug International, San Antonio, TX (USA). Technology Services Div.
• OSTI ID: 5401634
• Report Number(s): AD-A-209902/6/XAB
• Resource Relation: Other Information: Pub. in Health Physics, Vol. 56, No. 5, 671-682(May 1989)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
EYES
BIOLOGICAL RADIATION EFFECTS
ULTRAVIOLET RADIATION
ANIMAL TISSUES
BIOLOGICAL REPAIR
CORNEA
INJURIES
LASERS
NEAR ULTRAVIOLET RADIATION
PATHOLOGY
PHOTOCHEMICAL REACTIONS
PRIMATES
PROGRESS REPORT
RETINA
SPECTRA
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RECOVERY
BODY
BODY AREAS
CHEMICAL REACTIONS
DOCUMENT TYPES
ELECTROMAGNETIC RADIATION
FACE
HEAD
MAMMALS
ORGANS
RADIATION EFFECTS
RADIATIONS
RECOVERY
REPAIR
SENSE ORGANS
TISSUES
VERTEBRATES
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture