Kit for the selective labeling of red blood cells in whole blood with TC-99m
Patent
·
OSTI ID:7114501
This patent describes a kit for use in labeling with technetium-99m the red blood cells contained in a whole blood sample drawn from a patient. It comprises a container having therein under sterile conditions lyophilized stannous ions complexed with a tin complexing agent selected from the group consisting of alkali metal citrates, alkali metal glucoheptonates, alkaline earth metal citrates, alkaline earth metal glucoheptonates, alkali metal tartrates, alkali metal pyrophosphates, diethylenetriamine pentaacetic acid, organic diphosphonates, ethylenediaminetetraacetic acid, and dimercaptosuccinic acid, wherein the tin content is from 5 to 100 {mu}g, together with a tin complex stabilizer: a supply of an oxidizing agent: and a separate supply of a chelating agent for both stannic and stannous tin.
- Assignee:
- Associated Universities, Inc., Washington, DC (United States)
- Patent Number(s):
- A; US 5116597
- Application Number:
- PPN: US 7-182441
- OSTI ID:
- 7114501
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400703 -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHEMICAL PREPARATION
DIAGNOSTIC USES
ERYTHROCYTES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
SYNTHESIS
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOI
400703 -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHEMICAL PREPARATION
DIAGNOSTIC USES
ERYTHROCYTES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
SYNTHESIS
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOI