Interface for liquid chromatograph-mass spectrometer

Patent · Tue Sep 19 00:00:00 EDT 1989

OSTI ID:7070224

Andresen, B D; Fought, E R

A moving belt interface is described for real-time, high-performance liquid chromatograph (HPLC)/mass spectrometer (MS) analysis which strips away the HPLC solvent as it emerges from the end of the HPLC column and leaves a residue suitable for mass-spectral analysis. The interface includes a portable, stand-alone apparatus having a plural stage vacuum station, a continuous ribbon or belt, a drive train magnetically coupled to an external drive motor, a calibrated HPLC delivery system, a heated probe tip and means located adjacent the probe tip for direct ionization of the residue on the belt. The interface is also capable of being readily adapted to fit any mass spectrometer. 8 figs.

• DOE Contract Number: W-7405-ENG-48
• Assignee: Sepragen Corp., San Leandro, CA (United States)
• Patent Number(s): US 4867947; A
• Application Number: PPN: US 6-904953
• OSTI ID: 7070224
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
400105* -- Separation Procedures
CHROMATOGRAPHY
DESIGN
EQUIPMENT INTERFACES
EXTRACTION APPARATUSES
EXTRACTION COLUMNS
LIQUID COLUMN CHROMATOGRAPHY
MASS SPECTROMETERS
MEASURING INSTRUMENTS
OPERATION
REMOVAL
SEPARATION EQUIPMENT
SEPARATION PROCESSES
SOLVENTS
SPECTROMETERS