Deposition method for moving ribbon liquid chromatograph-mass spectrometer interfaces

Journal Article · Wed Apr 01 04:00:00 EST 1981 · Anal. Chem.; (United States)

OSTI ID:6342335

Smith, R D; Johnson, A L

The improved aerosol liquid deposition device developed for liquid chromatographs (LC) and mass spectrometers (MS) interface constructed at Pacific Northwest Laboratory can handle enhanced solvent flows. Besides this, analyses using the PNL LC-MS system have demonstrated improved peak shapes and transfer efficiencies for the more volatile compounds. These advantages are a direct result of the deposition method which results in very rapid evaporation without direct heating of the ribbon. Since this system is not equipped with a solids inlet probe, an absolute measure of transfer efficiency is not possible; however, significant improvements in the transfer of volatile compounds have been noted. Compounds with boiling points of approximately less than 180/sup 0/C, which are difficult to detect with conventional deposition-evaporation techniques, are readily observed by using aerosol deposition. The aerosol deposition method for moving ribbon LC-MS interfaces is clearly superior to existing practice. The method can be easily and inexpensively added to existing moving ribbon interfaces and results in improved liquid evaporation, LC-MS peak shapes, and transfer efficiency.

• Research Organization: Pacific Northwest Lab., Richland, WA
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6342335
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 53:4; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
AEROSOLS
CHROMATOGRAPHY
COLLOIDS
DEPOSITION
DESIGN
DISPERSIONS
EQUIPMENT
LIQUID COLUMN CHROMATOGRAPHY
PERFORMANCE
SEPARATION PROCESSES
SOLS