In vitro effect of fenthion on human lymphocytes

Journal Article · Thu Aug 01 04:00:00 EDT 1991 · Bulletin of Environmental Contamination and Toxicology; (United States)

DOI:https://doi.org/10.1007/BF01688658· OSTI ID:7050066

Rani, M V.U. ^[1]; Rao, M S ^[2]

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1. Bharathiar Univ., Coimbatore (India)
2. Osmania Univ., Hyderabad (India)

Fenthion is an organophosphorus insecticide which is extensively used in control of leaf hoppers, cutworms, mites on vegetable crops. It has been reported that organophosphorus pesticides cause a significant increase in sister chromatid exchanges in mammalian cell lines. A significant increase of chromosomal aberrations has been reported in rural population exposed to pesticides. Organosphosphorus pesticides malathion, diazinon, dimethoate, phosdrin and dursban induced sister chromatid exchanges in human lymphoid cells. Exchange type of aberration has been reported in fluoriculturist who were exposed to organophosphorus, organochlorine pesticides. In the present investigation an attempt has been made to evaluate the cytogenetic effect of fenthion in human lymphocyte cultures in vitro.

• OSTI ID: 7050066
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (United States), Journal Name: Bulletin of Environmental Contamination and Toxicology; (United States) Vol. 47:2; ISSN 0007-4861; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CELL CYCLE
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MAN
MATERIALS
MUTATIONS
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
PRIMATES
SOMATIC CELLS
VERTEBRATES