Estimating exposures to 2,3,7,8-TCDD. Draft report

Technical Report · Tue Mar 01 04:00:00 EST 1988

OSTI ID:7041348

This exposure assessment document provides a review and update of information related to exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). Several scenarios are constructed to illustrate how contaminated material from contaminated soil, various land-disposal situations, and municipal-waste incineration can result in exposure to 2,3,7,8-TCDD. Estimates are also provided to show what the human exposure and risk would be via inhalation, dermal contact, and ingestion of contaminated soil. Part One presents an update of previous work and an analysis of key issues related to exposure assessment for chlorinated dibenzo-p-dioxins with emphasis on 2,3,7,8-TCDD, such as the behavior of 2,3,7,8-TCDD in soil and sediment, bioavailability from soil, the use of pharmacokinetics for estimating 2,3,7,8-TCDD exposures, and plant uptake. Part Two addresses the application of exposure-assessment methods discussed in Part One, in evaluating 2,3,7,8-TCDD exposures from selected situations. Twenty different exposure scenarios, covering contaminated soil, landfills, and incineration are presented. Human exposure and risk calculations are then computed under each pathway for the different scenarios.

• Research Organization: Environmental Protection Agency, Washington, DC (USA). Office of Health and Environmental Assessment
• OSTI ID: 7041348
• Report Number(s): PB-88-231196/XAB
• Country of Publication: United States
• Language: English

Related Subjects

500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
510200* -- Environment
Terrestrial-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
AROMATICS
CHLORINATED AROMATIC HYDROCARBONS
DIOXIN
ENVIRONMENTAL EXPOSURE
EVALUATION
HALOGENATED AROMATIC HYDROCARBONS
HAZARDOUS MATERIALS
HETEROCYCLIC COMPOUNDS
INCINERATORS
INHALATION
INTAKE
MATERIALS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
RESPIRATION
RISK ASSESSMENT
SEDIMENTS
SOILS
TOXICITY