Effects of moxibustion on cellular immunocompetence of gamma-irradiated mice

Journal Article · Sun Jan 01 04:00:00 EST 1989 · American Journal of Chinese Medicine; (USA)

DOI:https://doi.org/10.1142/S0192415X89000243· OSTI ID:7006096

Hau, D M; Wu, J C; Chang, Y H; Hwang, J T ^[1]

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1. Institute of Chinese Medicine, Taichung (Taiwan)

The effects of moxibustion on cellular immunocompetence of gamma-irradiated mice were investigated in this study. A total of 240 male young mice (ICR strain), 6-8 weeks of age, were chosen and divided into three groups. Group A was the normal control. Group B, the experimental control, was treated with 400 rad whole body gamma-irradiation. Group C, the experimental group, was treated with moxibustion (MT) after being exposed to gamma-irradiation. Six to eight mice from each group were sacrificed on days 1, 5, 12, 19, 26 and 33 post-irradiation. The body and splenic weights of mice in each group were measured. The cellular immunocompetence was measured by {sup 3}H-thymidine uptake in each experimental mouse. The results revealed that 400 rad of gamma-ray irradiation inhibited the increase of body and splenic weights, and exerted a pronounced inhibitory effect on the incorporative rates of {sup 3}H-thymidine after being stimulated by mitogens such as PHA, PWM, Con A and LPS in the splenic lymphoid cells. MT seemed to help the recovery of the cellular immunocompetence in the gamma-ray irradiated mice.

• OSTI ID: 7006096
• Journal Information: American Journal of Chinese Medicine; (USA), Journal Name: American Journal of Chinese Medicine; (USA) Vol. 17:3-4; ISSN 0192-415X; ISSN AJCMB
• Country of Publication: United States
• Language: English

Related Subjects

551001 -- Physiological Systems-- Tracer Techniques
560152* -- Radiation Effects on Animals-- Animals
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
AZINES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DRUGS
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
GAMMA RADIATION
HETEROCYCLIC COMPOUNDS
IMMUNITY
IONIZING RADIATIONS
IRRADIATION
ISOTOPE APPLICATIONS
LEUKOCYTES
LYMPHOCYTES
MATERIALS
MITOGENS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRIMIDINES
RADIATIONS
RADIOSENSITIVITY EFFECTS
RADIOSENSITIZERS
RIBOSIDES
SOMATIC CELLS
SPLEEN
THYMIDINE
TRACER TECHNIQUES
WHOLE-BODY IRRADIATION