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Asymmetric unbridged nitrogen. 39. configurations and conformations of N-substituted perhydro-1,3,2 -dioxazines -

Journal Article · · Chem. Heterocycl. Compd. (Engl. Transl.); (United States)
OSTI ID:7005806

The stereochemical peculiarities of N-substituted perhydro-1,3,2-dioxazines were analyzed thoroughly on the basis of NMR spectroscopic data, the results of x-ray diffraction analysis, and quantitative MO theory. It is shown that in solutions and in the crystalline state these compounds exist in a ''chair'' conformation with an equatorial orientation of the substituents in the 2 and 4 positions; the high degree of crimped character of the heteroring (the angle of inflection along the 0...0 line is 70.3/sup 0/) is due to repulsion of the unshared electron pairs of the N and O atoms and n-o* interactions. An increase in the n-o* interaction in dialkoxy amines and acetals on passing from C /SUB s/ to C/sub 2/ symmetry of the molecules was demonstrated.

Research Organization:
Institute of Chemical Physics, Acad. of Sci., Chernogolovka
OSTI ID:
7005806
Journal Information:
Chem. Heterocycl. Compd. (Engl. Transl.); (United States), Journal Name: Chem. Heterocycl. Compd. (Engl. Transl.); (United States) Vol. 21:10; ISSN CHCCA
Country of Publication:
United States
Language:
English