Rapid brain scanning radiopharmaceutical

Patent · Mon Mar 02 23:00:00 EST 1987

OSTI ID:7000775

Sargent, III, T W; Shulgin, A T; Mathis, C A

A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula 1 is administered to one animal: as given in figure in patent wherein R[sub 1] and R[sub 2] are independently alkyl of 1 to 6 carbon atoms or benzyl; R[sub 3] is alkyl of 1 to 6 carbon atoms, benzyl, cyclopropylalkyl of 4 to 6 carbon atoms, or cyanoalkyl of 2 to 6 carbon atoms; R[sub 4] is hydrogen, benzyl or alkyl of 1 to 6 carbon atoms; with the provisos that R[sub 4] is not isopropyl and when R[sub 4] is methyl, R[sub 3] is not benzyl; and X is a radioactive halogen. 2 figs.

• DOE Contract Number: W-7405-ENG-48
• Assignee: Univ. of California, Berkeley, CA (United States)
• Patent Number(s): US 4647446; A
• Application Number: PPN: US 6-732517
• OSTI ID: 7000775
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD FLOW
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CHEMICAL PREPARATION
DIAGNOSTIC USES
DRUGS
IMAGE PROCESSING
LABELLED COMPOUNDS
NERVOUS SYSTEM
ORGANS
PROCESSING
RADIOPHARMACEUTICALS
SYNTHESIS
USES