Electrospray ionization phenomena and the interface of capillary electrophoresis and mass spectrometry. [Quaternary phosphonium salts]

Conference · Wed Jun 01 04:00:00 EDT 1988

OSTI ID:6956822

Smith, R D; Barinaga, C J; Udseth, H R

Recently a new electrospray ionization interface for capillary electrophoresis-mass spectroscopy (CE-MS) has been developed. The interface uses a sheath flow of liquid to make electrical contact at the CZE terminus, thus defining both the CZE and electrospray field gradients. Ions created by the ESI process are sampled through a 1 mm nozzle into a region mechanically pumped at 50 L/s using a single-stage roots blower. The ions entering this region are sampled through a 2 mm dia skimmer orifice located 0.5 cm behind the nozzle orifice. Ions passing through the skimmer enter a radio frequency focusing quadrupole. This region is pumped by a cryopump. A mixture of four quaternary phosphonium salts is used to illustrate capillary electrophoresis separations with mass spectroscopy and their uses. 2 figs.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6956822
• Report Number(s): PNL-SA-15664; CONF-8806199-4; ON: DE88014080
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
BLOOD VESSELS
BODY
CAPILLARIES
CARDIOVASCULAR SYSTEM
DISPERSIONS
ELECTROPHORESIS
IONIZATION
MASS SPECTROSCOPY
MIXTURES
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
SEPARATION PROCESSES
SPECTROSCOPY
SPRAYS